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The use of lisinopril/hydrochlorothiazide is not indicated in patients requiring dialysis for renal failure.

This product may rarely cause seriouspossibly fatalliver problemsGet medical help right away if you have any symptoms of liver damagesuch asnausea/vomiting that doesn’t stoploss of appetitestomach/abdominal painyellowing eyes/skindark urine.

Angioedema of the faceextremitieslipstongueglottis and/or larynx has been reported uncommonly in patients treated with ACE inhibitorsincluding lisinoprilThis may occur at any time during therapyIn such caseslisinopril should be discontinued promptly and appropriate treatment and monitoring should be instituted to ensure complete resolution of symptoms prior to dismissing the patientEven in those instances where swelling of only the tongue is involvedwithout respiratory distresspatients may require prolonged observation since treatment with anti-histamines and corticosteroids may not be sufficient.

There is limited experience with hydrochlorothiazide during pregnancyespecially during the first trimesterAnimal studies are insufficient.

Hydrochlorothiazide crosses the placentaBased on the pharmacological mechanism of action of hydrochlorothiazide its use during the second and third trimester may compromise foeto-placental perfusion and may cause foetal and neonatal effects like icterusdisturbance of electrolyte balance and thrombocytopenia.

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2018-10-03T07:24:24+00:00 2018 - 09 - 11|

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