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Since untreated mental/mood problemssuch as depressionpanic attacksobsessive compulsive disordercan be a serious conditiondo not stop taking this medication unless directed by your doctorIf you are planning pregnancybecome pregnantor think you may be pregnantimmediately discuss the benefits and risks of using this medication during pregnancy with your doctor.
Families and caregivers of patients being treated with antidepressants for Major Depressive Disorder or other indicationsboth psychiatric and nonpsychiatricshould be alerted about the need to monitor patients for the emergence of agitationirritabilityunusual changes in behaviorand the other symptoms described aboveas well as the emergence of suicidalityand to report such symptoms immediately to health care providersSuch monitoring should include daily observation by families and caregiversPrescriptions for SARAFEM should be written for the smallest quantity of tablets consistent with good patient managementin order to reduce the risk of overdose.
The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIsincluding SARAFEMalone but particularly with concomitant use of other serotonergic drugsincluding triptanstricyclic antidepressantsfentanyllithiumtramadoltryptophanbuspironeand StJohn’s Wortand with drugs that impair metabolism of serotoninin particularMAOIsboth those intended to treat psychiatric disorders and also otherssuch as linezolid and intravenous methylene blue
It should be noted that the diagnosis of PMDD does exist during pregnancyFluoxetine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetusAll pregnancies have a background risk of birth defectslossor other adverse outcome regardless of drug exposure.
Drug interactions may change how your medications work or increase your risk for serious side effectsThis document does not contain all possible drug interactionsKeep a list of all the products you useincluding prescription/nonprescription drugs and herbal productsand share it with your doctor and pharmacistDo not startstopor change the dosage of any medicines without your doctor’s approval.
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