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‘Tension type headacheis the most common type of headache experienced by most of us in our life.
There are no adequate and well-controlled studies in pregnant womenthereforerizatriptan should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.
As with other 5-HT1 agonistssensations of tightnesspainpressureand heaviness in the precordiumthroatneck and jaw commonly occur after treatment with rizatriptan and are usually noncardiac in originHoweverif a cardiac origin is suspectedpatients should be evaluatedPatients shown to have CAD and those with Prinzmetal’s variant angina should not receive 5-HT1 agonists.
Serious cardiac eventsincluding some that have been fatalhave occurred following use of 5-HT 1 agonistsThese events are extremely rare and most have been reported in patients with risk factors predictive of CADEvents reported have included coronary artery vasospasmtransient myocardial ischaemiamyocardial infarctionventricular tachycardia and ventricular fibrillation.
The administration of rizatriptan with other 5-HT 1 agonistse.gsumatriptanzolmitriptannaratriptanhas not been evaluated in migraine patientsBecause their vasospastic effects may be additiveco-administration of rizatriptanand other 5-HT 1 agonists within 24 hours of each other is not recommended.
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