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The man’s central nervous system stimulates the release of a number of chemicalsincluding nitric oxidewhich is essential for producing and maintaining an erectionNitric oxide stimulates the production of cyclic GMPa chemical that relaxes the smooth muscles in the penisThis allows blood to flow into the tiny pool-like cavernous sinusesflooding the penisThis increased blood flow nearly doubles the diameter of the spongy chambersThe veins surrounding the chambers are squeezed almost completely shut by this pressureThe veins are unable to drain blood out of the penis and so the penis becomes rigid and erectAfter ejaculation or climaxcyclic GMP is broken down by an enzyme called phosphodiesterase-5pde5causing the penis to become flaccidunerectagainImportant substances for erectile health.
This drug may be used as part of a combination therapyThat means you need to take it with other drugs.
Dutasteride is sometimes given with another medication called tamsulosinFlomaxBe sure to read the medication guide or patient instructions provided with each of your medications.
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in human serum following dosing to steady state, unchanged dutasteride, 3 major metabolites 4 -hydroxydutasteride, 1,2-dihydrodutasteride, and 6-hydroxydutasteride , and 2 minor metabolites 6,4 -dihydroxydutasteride and 15-hydroxydutasteride , as assessed by mass spectrometric response, have been detected.