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No dosage adjustment is necessary for patients with mild or moderate renal impairmentLexapro should be used with caution in patients with severe renal impairment.

A major depressive episode may be the initial presentation of bipolar disorderIt is generally believedthough not established in controlled trialsthat treating such an episode with an antidepressant alone may increase the likelihood of precipitation of a mixed/manic episode in patients at risk for bipolar disorderWhether any of the symptoms described above represent such a conversion is unknownHoweverprior to initiating treatment with an antidepressantpatients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disordersuch screening should include a detailed psychiatric historyincluding a family history of suicidebipolar disorderand depressionIt should be noted that Lexapro is not approved for use in treating bipolar depression.

Children may be more sensitive to the side effects of this drugespecially loss of appetite and weight lossMonitor weight and height in children who are taking this drug.

Patientstheir familiesand their caregivers should be encouraged to be alert to the emergence of anxietyagitationpanic attacksinsomniairritabilityhostilityaggressivenessimpulsivityakathisiapsychomotor restlessnesshypomaniamaniaother unusual changes in behaviorworsening of depressionand suicidal ideationespecially early during antidepressant treatment and when the dose is adjusted up or downFamilies and caregivers of patients should be advised to look for the emergence of such symptoms on a day-to-day basissince changes may be abruptSuch symptoms should be reported to the patient’s prescriber or health professionalespecially if they are severeabrupt in onsetor were not part of the patient’s presenting symptomsSymptoms such as these may be associated with an increased risk for suicidal thinking and behavior and indicate a need for very close monitoring and possibly changes in the medicationsee WARNINGS AND PRECAUTIONS

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2018-10-13T13:13:00+00:00 2018 - 09 - 14|

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