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Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levelsAvoid foods that have a high level of tyraminesuch as:

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotoninExamples include street drugs such as MDMAecstasyStJohn’s wortcertain antidepressantsincluding mirtazapineSSRIs such as fluoxetine/paroxetineSNRIs such as duloxetine/venlafaxinetramadolcertaintriptansused to treat migraine headachessuch as rizatriptansumatriptanzolmitriptanamong othersThe risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

As documented with other antibiotics when used in patients with difficult to treat infections and/or for prolonged periodsemergent decreases in susceptibility have been observed with linezolidResistance to linezolid has been reported in enterococciStaphylococcus aureus and coagulase negative staphylococciThis generally has been associated with prolonged courses of therapy and the presence of prosthetic materials or undrained abscessesWhen antibiotic-resistant organisms are encountered in the hospital it is important to emphasize infection control policies.

The duration of treatment is dependent on the pathogenthe site of infection and its severityand on the patient’s clinical response.

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2018-10-03T07:22:41+00:00 2018 - 09 - 11|

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