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Seizures have been reported during overdose and with withdrawal from lioresal intrathecal as well as in patients maintained on therapeutic doses of lioresal intrathecal.

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Children should be of sufficient body mass to accommodate the implantable pump for chronic infusionPlease consult pump manufacturer’s manual for specific recommendations.

Pharmacokinetics of LIORESAL INTRATHECALThe pharmacokinetics of CSF clearance of LIORESAL INTRATHECAL calculated from intrathecal bolus or continuous infusion studies approximates CSF turnoversuggesting elimination is by bulk-flow removal of CSF.

Pharmacodynamics of LIORESAL INTRATHECAL Intrathecal BolusAdult PatientsThe onset of action is generally one-half hour to one hour after an intrathecal bolusPeak spasmolytic effect is seen at approximately four hours after dosing and effects may last four to eight hoursOnsetpeak responseand duration of action may vary with individual patients depending on the dose and severity of symptoms.

If you miss a dosetake it as soon as you rememberIf it is near the time of the next doseskip themissed doseTake your next dose at the regular timeDo not double the dose to catch up.

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2018-10-13T14:23:59+00:00 2018 - 09 - 10|

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