As for the difference between the oral version and emsam, it runs like this as far as i understand it the transdermal patch allows for 74 bioavailability, meaning as i understand it it s in the blood and active.
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Apply a skin patch as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not use extra patches to make up the missed dose.
Drug interactions may change how your medications work or increase your risk for serious side effectsThis document does not contain all possible drug interactionsKeep a list of all the products you useincluding prescription/nonprescription drugs and herbal productsand share it with your doctor and pharmacistDo not startstopor change the dosage of any medicines without your doctor’s approval.
Tell your doctor or pharmacist if you are using any of these medications beforeduringor within 2 weeks after treatment with selegilineTell your doctor or pharmacist if you have taken fluoxetine during at least 5 weeks before starting selegilineDiscuss with your doctor how much time to wait between starting or stopping any of these drugs and taking selegiline.
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per 24 hours and the results from the phase i tyramine challenge study in fed volunteers administered emsam 12 mg per 24 hours, patients receiving these doses should follow dietary modifications required for patients taking emsam 9 mg per 24 hours and 12 mg per 24 hours see warnings and precautions 5.