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Elevated systolic or diastolic pressure causes increased cardiovascular riskand the absolute risk increase per mmHg is greater at higher blood pressuresso that even modest reductions of severe hypertension can provide substantial benefitRelative risk reduction from blood pressure reduction is similar across populations with varying absolute riskso the absolute benefit is greater in patients who are at higher risk independent of their hypertensionfor examplepatients with diabetes or hyperlipidemiaand such patients would be expected to benefit from more aggressive treatment a lower blood pressure goal.
When pregnancy is detecteddiscontinue Benicar as soon as possiblesee WARNINGS AND PRECAUTIONSDrugs that act directly on the renin-angiotens in system can cause injury and death to the developing fetussee WARNINGS AND PRECAUTIONS]
Some antihypertensive drugs have smaller blood pressure effectsas monotherapyin black patientsand many antihypertensive drugs have additional approved indications and effectse.gon anginaheart failureor diabetic kidney diseaseThese considerations may guide selection of therapy.
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the major thrust of this promotional campaign, which involved distributing marketing materials to physicians and consumers, was that benicar and benicar hct were superior, more effective, and safer than other available blood pressure drugs.